Is berberine a good substitute for metformin?

Studies show that taking berberine can lower blood sugar levels to a similar extent as the popular diabetes drug metformin ( 4 ). In a study in 116 people with type 2 diabetes, the substance reduced fasting blood sugar levels by 20% and HbA1c (a marker for long-term blood sugar levels) by 12% ( 5 ).

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Is berberine harmful to kidneys?

Berberine (BBR) has been shown to have antifibrotic effects in liver, kidney and lung. However, the mechanism of cytoprotective effects of BBR in DN is still unclear. In respect to this, is berberine a stimulant? The results (Table 1) indicate that among these stimulants, berberine induces the most robust activation of glucose uptake and that its effects are not enhanced by the other stimulants. This suggests that the mechanism of berberine activation shares common steps with both pathways.

People also ask does berberine lower blood sugar?

Berberine is a supplement that emerging research has shown can be effective in treating type 2 diabetes because of its blood-sugar-lowering properties. It's generally well tolerated and affordable, and it can be effective for some people, but it's not without side effects and risks. How do bodybuilders use berberine? As a bodybuilder, it's recommended to take between 1-1.5g of berberine a day, divided into 2-3 servings, and taken with meals. After 3-4 months, take a break to protect your gut from berberine's antibiotic effect.

Then, how much does berberine lower cholesterol?

In a 2-month study of 63 patients, berberine 500 mg twice daily lowered LDL by an average of 23.8%, and a combination of simvastatin 20 mg daily and berberine lowered LDL by an average of 31.8%.