Drugs Forum
Is vinpocetine banned?
In the United States, vinpocetine is not regulated in the neutraceutical industry, and it is often included as an active ingredient in dietary supplements. Vinpocetine is banned from Australia, New Zealand, and Canada due to potential harmful nootropic characteristics as a cognitive enhancing supplement [1–3].
Correspondingly, is vinpocetine legal?
The U.S. Food & Drug Administration (FDA) has made a tentative ruling that vinpocetine, a synthetic compound derived from vincamine, does not meet the requirements of a dietary ingredient and therefore cannot be legally used in dietary supplements. And another question, what does vinpocetine do in the brain? Vinpocetine inhibits PDE1 activity and improves cerebral blood flow by elevating cGMP and cAMP, increasing mitochondrial function, and improving glucose and oxygen utilization by the brain. Vinpocetine helps improve spatial memory in rats by preventing neuronal damage and favorably modulating cholinergic function ( 18 ).
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