Can memantine make Alzheimer's worse?

However, the worsening of psychotic symptoms in patients with Lewy body dementia (LBD) treated with memantine has been recently reported. We describe three patients with probable Alzheimer's disease who developed worsening or de novo visual hallucinations and agitation after memantine treatment.

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In respect to this, what is the best drug for dementia?

The cholinesterase inhibitors most commonly prescribed are: Donepezil (Aricept®): approved to treat all stages of Alzheimer's disease. Rivastigmine (Exelon®): approved for mild-to-moderate Alzheimer's as well as mild-to-moderate dementia associated with Parkinson's disease. People also ask which is better donepezil or memantine? Donepezil showed an advantage over memantine in mild-to-moderate AD, whereas memantine was more effective than donepezil in severe AD. The combination therapy of memantine plus donepezil achieved better outcomes than placebo in the CGI.

Keeping this in consideration, does memantine cause weight loss?

found that memantine could significantly suppress the appetite and binge-eating disorder and finally decrease the body weight within a few days (5). You can also ask can memantine cause seizures? In clinical trials of NAMENDA, seizures occurred in 0.2% of patients treated with NAMENDA and 0.5% of patients treated with placebo.

Is memantine for mild dementia?

Memantine, indicated for moderate to severe Alzheimer disease (AD), is frequently prescribed off-label either alone or with a cholinesterase inhibitor for mild AD and mild cognitive impairment. In 2006, it was prescribed to 19% of patients with mild AD in the United States.