What is 2-hydroxypropyl-β-cyclodextrin used for?

2-Hydroxypropyl-β-cyclodextrin (HP-β-CD) is a chemically modified derivative of β-cyclodextrin that exhibits an enhanced safety profile compared with its naturally occurring parent compound (4). HP-β-CD is used as an excipient for cardiac dysrhythmia, inflammation, and fungal disease medications (6).

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What will dissolve cholesterol?

Cyclodextrin Dissolves Cholesterol Crystals So They Can Be Excreted by Body; Reduces Arterial Wall Inflammation. Can olive oil remove plaque from arteries? (Reuters Health) - A traditional Mediterranean diet with added olive oil may be tied to a lower risk of heart disease at least in part because it helps maintain healthy blood flow and clear debris from arteries, a Spanish study suggests.

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Is cyclodextrin safe for humans? Cyclodextrins alone are poorly absorbed transdermally, but in combination with absorption-promoting agents, they are able to permeate the skin by 12%, 43%, and 53% for β-CD, RM-β-CD, and HP-β-CD, respectively. Concentrations up to 0.1% of α-, β-, and γ-cyclodextrins are considered safe.

Is beta cyclodextrin the same as cyclodextrin?

Beta-cyclodextrin is the least soluble cyclodextrin in water. In β-cyclodextrin, the C2 and C3 hydroxyl groups of adjacent α-D-glucopyranosyl units orientate in such a way as to have maximum interaction with each other, compared to the other cyclodextrins. Consequently, how do cyclodextrins work? Cyclodextrins form a toroid (truncated cone) configuration with multiple hydroxyl groups at each end. This allows them to encapsulate hydrophobic compounds without losing their solubility in water. Among other applications, cyclodextrins can be used to carry hydrophobic drug molecules into biological systems.