Can citrulline cause headaches?

Nitrates (drugs that increase the blood flow to the heart): Taking nitrate medications (often used to treat angina) along with citrulline may result in an increase in blood flow to the heart that could cause side effects such as headaches, flushing, dizziness, fainting, low blood pressure (hypotension), or irregular

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Also, does l-citrulline have side effects?

There are no reported side effects of L-citrulline. However, the supplement may affect the way certain drugs work in your body. Do not take this supplement if you are taking: Nitrates for heart disease. Accordingly, what happens if you take too much citrulline? Many athletes take L-Citrulline to improve their workout by increasing blood flow to muscle mass. However, taking too much of the nonessential amino acid can be dangerous. This is because the medication is known to increase nitric oxide levels and dilate blood vessels that lower the body's blood pressure.

Also, is l-citrulline good for the brain?

-Citrulline is a neutral amino acid and a major precursor of L-arginine in the nitric oxide (NO) cycle. Recently it has been reported that L-citrulline prevents neuronal cell death and protects cerebrovascular injury, therefore, L-citrulline may have a neuroprotective effect to improve cerebrovascular dysfunction. People also ask should i take citrulline malate on off days? WHEN SHOULD I TAKE IT? Citrulline Malate is best taken on an empty stomach for optimal absorption. On exercise days we would recommend taking one serving first thing in the morning and another serving 30-40 minutes prior to exercise.

How much citrulline is too much?

Overall, the study indicated that doses greater than 10 grams are unnecessary. Blood analysis performed in participants after they took citrulline supplements did not show any negative changes to normal body functions or blood pressure. Summary: Based on current information, citrulline is safe and well-tolerated.