What does Dynamin 2 do?

Given that the best-known role of dynamin-2 is to catalyze membrane scission during endocytosis, most of the studies regarding the mechanism underlying CNM associated to mutations in dynamin-2 have been focused in this cellular process. Dhuʻl-Q. 12, 1434 AH

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Regarding this, is dynamin a protein?

Dynamin is a 100-kDa protein macromolecule, belonging to the superfamily of GTPases, which plays a major role in synaptic vesicle transport. Members of the dynamin family are found throughout the eukaryotic kingdom. And another question, what is central nuclear myopathy? Collapse Section. Centronuclear myopathy is a condition characterized by muscle weakness (myopathy) and wasting (atrophy ) in the skeletal muscles, which are the muscles used for movement. The severity of centronuclear myopathy varies among affected individuals, even among members of the same family.

Regarding this, is dynamin in the golgi?

(1998) Science 279, 573–577] reported that dynamin II is localized in the trans-Golgi network (TGN) and involved in the formation of constitutive transport vesicles and clathrin-coated vesicles from this compartment. What is dynamin made of? Dynamin is a 100 kDa GTPase composed of the GTPase domain, the stalk consisting of a long four helix bundle, a bundle signaling element (BSE), which is a flexible connector between the GTPase domain and the stalk, a phosphoinositide-4,5-bisphosphate (PIP2)-binding pleckstrin homology (PH) domain, which is connected to

Regarding this, is dynamin part of the vesicle coat?

Dynamin is a protein required for vesicle formation during synaptic vesicle endocytosis (SVE) and for clathrin-mediated endocytosis. It is part of a family of large guanosine triphosphatases (GTPases), including classical dynamins, dynamin-like protein, optic atrophy 1 (OPA1), and mitofusin.