Is dynamin a motor protein?

Dynamin, like most motors, is a large protein , around 100 kDa, has a low affinity for nucleotide, a high rate of hydrolysis, and readily releases the hydrolyzed nucleotide.

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And another question, what is dynamin made of?

Dynamin is a 100 kDa GTPase composed of the GTPase domain, the stalk consisting of a long four helix bundle, a bundle signaling element (BSE), which is a flexible connector between the GTPase domain and the stalk, a phosphoinositide-4,5-bisphosphate (PIP2)-binding pleckstrin homology (PH) domain, which is connected to What do different dynamin mutations do? Dynamin-2 is a ubiquitously expressed GTP-ase that mediates membrane remodeling. Recent findings indicate that dynamin-2 also regulates actin dynamics. Mutations in dynamin-2 cause dominant centronuclear myopathy (CNM), a congenital myopathy characterized by progressive weakness and atrophy of skeletal muscles.

Also, what do synaptotagmins do?

The synaptotagmins are a family of proteins with an N-terminal transmembrane domain and two cytoplasmic C2 domains (see family members). Synaptotagmin-1 is localized to synaptic vesicles and is the trigger for their calcium-induced exocytosis. Where is Drp1 located? mitochondria Immunofluorescence and subcellular fractionation show that endogenous Drp1 is localized to mitochondria, which is also consistent with a role in mitochondrial division.

And another question, what is dnm1 mutation?

Epileptic encephalopathy, caused by mutations in the dynamin-1 (DNM1; NM_004408) gene, is a newly identified neurologic disorder in children. Thus far, the full clinical and electroencephalographic features of children with DNM1 mutation-related epileptic encephalopathy have not been established. Consequently, is dynamin in the golgi? (1998) Science 279, 573–577] reported that dynamin II is localized in the trans-Golgi network (TGN) and involved in the formation of constitutive transport vesicles and clathrin-coated vesicles from this compartment.