Can you take 2000 mg of berberine a day?

How to Use It: Berberine Dosage. The standard berberine dosage is 900 to 2,000 mg per day, spread out over three or four doses. “I recommend taking it about 10 to 20 minutes before meals, so that it will have maximum effect,” Dr. Blum says.

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Can berberine cause shortness of breath?

Standard doses of berberine are generally well tolerated and eventual adverse events are rare and mild. On the contrary, high doses have been associated with arterial hypotension, dyspnea, flu-like symptoms, gastrointestinal discomfort, constipation, and cardiac damage. Accordingly, can berberine cause depression? The effect of berberine on neurotrophic factors in depression. An antidepressant effect of berberine results from elevation of brain‐derived neurotrophic factor (BDNF) levels.

Can berberine cause liver damage?

Sub-chronic toxicity of berberine has reported to damages lung and liver by increasing alanine aminotransferase (ALT) and aspartate aminotransferase (AST), significantly (Ning et al., 2015). How long can I stay on berberine? When taken by mouth: Berberine is possibly safe for most adults. It's been used safely in doses up to 1.5 grams daily for 6 months.

Accordingly, does berberine speed up metabolism?

Berberine has been reported as a critical factor in promoting adaptive thermogenesis through activating BAT activity. Animal experiments showed that berberine (5 mg/kg body weight) administration increased whole-body energy expenditure by 20% without changes in physical activity.